Prof. Dr. Sundeep Mishra evaluates Mavacamten, a first-in-line allosteric inhibitor molecule to target the specific molecular defect of hypertrophic cardiomyopathy. He also explores the results of both EXPLORER-HCM and MAVERICK-HCM trials that tested the benefit of this drug.
Aug 24, 2020
Dr. Sundeep Mishra in his exclusive COVID-19 series for M3 India details on the role of micronutrients and their supportive role in prevention and treatment of the infection. He also provides his opinion on herbal supplements being marketed as immunity boosters.
Aug 14, 2020
"Doctor, can simple daily steam inhalation prevent COVID infection?": Prof. Dr. Sundeep Mishra an...
Prof. Dr. Sundeep Mishra clarifies frequently asked patient questions on whether steam inhalation and saline gargles help in COVID-19 and if so, which stages of the disease would they prove particularly useful. He also takes us through COVID-19 pathogenesis and timeline from exposure to onset.
Jul 24, 2020
Wondering how to increase your OPD numbers? Explore these ten smart ways highlighted by Prof. Dr. Sundeep Mishra to increase patient volume and help physicians build their medical practice successfully.
Jul 17, 2020
Dr. Sundeep Mishra answers questions on prescribing two medications- chloroquine and hydroxychloroquine, currently being used as prophylactic therapies in the fight against COVID-19.
Jul 10, 2020
Dr. Sundeep Mishra details on new biomarkers in heart failure that can serve as essential indicators for diagnosis, prognosis, risk stratification, therapeutic targeting, and therapeutic guidance.
Jul 02, 2020
As unlock 1.0 begins in the country, Prof. Dr. Sundeep Mishra writes on essential actions and precautions doctors looking to re-start their OPD should take to ensure smooth functioning of their practice.
Jun 09, 2020
Biomarkers provide prognostic information about the disease, which then aids clinicians in deciding how aggressively they need to treat the disease. Here, Dr. Sundeep Mishra covers the various new biomarkers and their importance in the diagnosis of ACS.
May 11, 2020
Dr. Sundeep Mishra writes on the ketogenic diet, its benefits apart from weight loss, particularly studies that have dealt with the positive effects it may have for patients with diabetes and risk factors for CAD.
Mar 05, 2020
Dr. Sundeep Mishra opines on the results of the ISCHEMIA trial that challenged the current practice of percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) along with optimal medical therapy (OMT) for coronary artery disease patients.
Feb 18, 2020
As part of the Sunday series, we bring to you an article from archives where Prof. Dr. Sundeep Mishra writes about the effects of air pollution on heart health and smog being a major contributor to the rise in cardiovascular disease and mortality.
Dec 29, 2019
Does bag mask ventilation (BMV) during endotracheal intubation (ETI) prevent hypoxemia in the cri...
Does BMV during tracheal intubation of critically ill adults prevent hypoxemia without increasing the risk of aspiration following administration of an induction agent- until the time by which intubation happens? Prof. Dr. Sundeep Mishra assesses the risk-benefit for this strategy.
Nov 19, 2019
Take the poll: Can we use Beta-Blockers in COPD patients with/without heart disease?: Prof. Dr. S...
There is a general apprehension regarding prescription of beta-blockers to COPD patients with or without the existence of heart disease, largely due to fear of adverse reactions. Prof. Dr. Sundeep Mishra in this article, deliberates on this question and gives his take on the subject.
Nov 11, 2019
In addition to numerous contributing factors and comorbidities, influenza and pneumococcal infections are also responsible for worsening outcomes in patients with CVD. Here, Prof. Dr. Sundeep Mishra elaborates on important immunisation options to be recommended to such patients.
Oct 07, 2019
Although angioplasty is a quick solution to ACS or angina, in reality atherosclerosis is a progressive disease and one can only retard its progression through healthy diet and exercise. Here, Dr. Sundeep Mishra provides dietary and exercise tips that doctors can give patients post angioplasty.
Sep 19, 2019
Key takeaways from 3 major trials covered at ESC 2019 Congress for Indian Cardiologists: Dr. Sund...
Prof. Dr. Sundeep Mishra reviews three major studies presented at this year's European Society of Cardiology (ESC) 2019 Congress and provides key takeaways for Indian Cardiologists.
Sep 06, 2019
Dr. Sundeep Mishra offers his expert commentary on the late breaking results from DAPA HF trial which sought to investigate whether dapagliflozin would prove useful in treating patients with heart failure, even in the absence of diabetes.
Sep 04, 2019
Prof. Dr. Sundeep Mishra discusses the diagnosis and treatment modality of heart failure with preserved ejection fraction based on the ESC 2016 and American Society of Echocardiography and European Association of Cardiovascular Imaging guidelines in 2016.
Aug 01, 2019
In the Sunday Series today we bring to you a popular article from our archives where Prof. Dr. Sundeep Mishra writes about low sodium salts and why they should never be recommended as a substitute to regular salt to hypertensive, diabetic, and renal disease patients.
Jul 28, 2019
CABG in Ischaemic Heart Failure- 'To STICH it or not, that is the question!': Prof. Dr. Sundeep M...
Prof. Dr. Sundeep Mishra critically analyses the STICH trial which showed the long-term benefit of CABG in terms of lowering the overall mortality from any cause in patients of ischaemic cardiomyopathy.
Jul 17, 2019
'Can TAVR become an alternative to surgical valve replacement in younger, low-risk patients?'- Dr...
Prof. Dr. Mishra mentions that, though classically, SAVR is the gold-standard in younger patients, and TAVR restricted to only older patients, a careful selection of patients and valve type may lead to dramatic reduction in complications, making TAVR an alternate for low-risk, younger patients too.
Jun 24, 2019
In the Suday Series here is an article from Prof. Dr. Sundeep Mishra where he discusses role of fat in coronary artery disease based on clinical trials.
Jun 23, 2019
Various trials have confirmed the efficacy of CoQ10 leading to significant improvement in clinical and haemodynamic parameters and exercise tolerance in patients. In this write-up, Dr. Sundeep Mishra focusses on the use of CoQ10 in heart failure, statin intolerance, and hypertension.
Jun 07, 2019
Dr. Sundeep Mishra writes that several factors need to be taken into account while prescribing therapy for hypertension, diurnal variation of BP being one such variable for which the drug Diltiazem proves particularly effective.
May 21, 2019
Dr. Sundeep Mishra critiques the new ACC/AHA guidelines by analysing the key messages- lifestyle modification being the main focus, discussing the dismissal of aspirin, pointing out its overall limitations.
Mar 28, 2019
2019 ACC AHA guidelines -Aspirin not useful in primary prevention of CAD: Prof. Sundeep Mishra's ...
In the light of the recent 2019 ACC/AHA guideline recommendation on limited use of Asprin for the primary prevention of of cardiovascular disease, we are re-publishing Dr. Sundeep Mishra's view for the Indian doctors.
Mar 21, 2019
Prof. Dr. Sundeep Mishra shares the learning from Cardiovascular Inflammation Reduction Trial (CIRT), presented at the Annual AHA Meeting 2018 and sought to investigate whether suppression of inflammation with low-dose methotrexate could prevent CV events in patients with stable CVD.
Jan 14, 2019
Main teachings from the first ever interventional cardiology workshop at NIC- CSI 2018: Dr. Sunde...
This time the Annual CSI Meeting was held in MMRDA Grounds, Mumbai, 22-25th November 2018. The whole event was undertaken in a pre-fabricated venue which is perhaps a first of its kind in India. In this article, Prof. Sundeep Mishra summarises the main teachings of the workshop.
Nov 30, 2018
What the new AHA / ACC Lipid Guidelines mean for India– Praise, reproach and puzzlement-Prof. Sun...
In the recently concluded American Heart Association (AHA) annual scientific session which was held in Chicago, November 10-12, 2018 new cholesterol-lowering guidelines were presented and simultaneously published online in the “Circulation” and “Journal of American College of Cardiology” journal.
Nov 17, 2018
Prof. Sundeep Mishra helps throws light on the REDUCE-IT trial, presented at the recent annual AHA Session 2018, and explains how it may affect the practice of physicians.
Nov 16, 2018