Age-related macular degeneration (AMD) is a condition affecting older people and involves the loss of the person's central field of vision. 

It occurs when the macular (or central) retina develops degenerative lesions. It is thought that circulatory insufficiency, with reduction in the blood flow to the macular area, also plays a part. Several forms of AMD exist. Globally, AMD ranks third as a cause of blindness after cataract and glaucoma. It is the primary cause in industrialized countries. The main risk factor is ageing. Other risk factors may include the use of tobacco, genetic tendencies, the degree of pigmentation (with light coloured eyes being at higher risk), arterial hypertension, the ultraviolet rays, and consumption of a non-balanced diet. The early and intermediate stages of AMD usually start without symptoms. Only a comprehensive dilated eye exam can detect AMD. The eye exam may includes visual acuity test, dilated eye exam, Amsler grid.