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The implications of dysglycaemia on aerobic exercise and ventilatory function in cystic fibrosis

Journal of Cystic Fibrosis Nov 13, 2019

Causer AJ, Shute JK, Cummings MH, et al. - Among adults with cystic fibrosis (CF) (n = 46; age: 26.9 y; forced expiratory volume in 1s: 65.3%; 26 males), who had received a diagnosis of CF-related diabetes (CFRD) (n = 19), impaired glucose tolerance (n = 8) or normal glucose tolerance (n = 19), researchers examined cardiopulmonary exercise and glycaemic control tests in order to determine if the development of CFRD is related to a reduced aerobic fitness in adults with more severe lung disease. Findings revealed reduced maximal oxygen uptake in adults with CF-related dysglycaemia vs age- and gender-matched counterparts, this was attributed to a greater degree of CF lung disease in these populations.
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