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Testing the performance of a prototype lateral flow device using bronchoalveolar lavage fluid for the diagnosis of invasive pulmonary aspergillosis in high-risk patients

Mycoses Sep 20, 2017

Castillo CG, et al. - The specificity and sensitivity of the prototype lateral flow device (LFD) and the galactomannan (GM) enzyme immunoassay underwent comparative analysis in bronchoalveolar lavage (BAL) fluid in high-risk patients. There did not appear to be any improvement in the performance by using both tests. Among patients at risk for invasive pulmonary aspergillosis (IPA), the diagnostic performance of LFD and GM in BAL fluid were comparable. High specificity was noted with a poor sensitivity of both LFD and GM.
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