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Stroke care and case fatality in people with and without schizophrenia: A retrospective cohort study

BMJ Open Jun 14, 2021

Kapral MK, Kurdyak P, Casaubon LK, et al. - Using linked clinical and administrative databases, researchers conducted this retrospective cohort study to determine the connection between schizophrenia and stroke case fatality, adjusting for baseline features, stroke severity and processes of care. Between April 1, 2002, and March 31, 2013, 52,473 patients hospitalized with acute stroke were analyzed, 612 (1.2%) of whom had schizophrenia. People with schizophrenia were less likely to undergo thrombolysis, carotid imaging, rehabilitation, or be treated with antihypertensive, lipid-lowering, or anticoagulant therapies when compared with those without schizophrenia. Schizophrenia is linked to an increase in stroke case fatality, which cannot be fully explained by stroke severity, measurable comorbid conditions, or care processes.

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