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Serum squamous cell carcinoma antigen in psoriasis: A potential quantitative biomarker for disease severity

Dermatology Jun 09, 2018

Sun Z, et al. - In psoriasis patients, quantitative exploration of serum biomarkers in association with disease severity and treatment response was carried out, with a focus on serum squamous cell carcinoma antigen (SCCA). They obtained quantitative body surface area (qBSA) from standardized digital body images of the patients, and the psoriasis area severity index (PASI) was also monitored at different visits before and after treatment. Compared to the normal control group, the serum SCCA level in the psoriasis group was significantly higher. As per data, for psoriasis disease severity, the utility of serum SCCA was noted. Findings suggested a good association of the SCCA level with PASI and qBSA.
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