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Rituximab was effective for treatment of anti–N-Methyl-d-Aspartate receptor encephalitis in early adolescence in initially suspected dissociative disorder

Clinical Neuropharmacology May 28, 2021

Shibata T, Kawai H, Sakamoto S, et al. - Researchers present a case of an adolescent female patient with anti-Anti–N-methyl-d-aspartate receptor encephalitis who was initially suspected of having dissociative disorder but was responsive to immunotherapies including rituximab. Her symptoms and electroencephalogram findings were proportional to the antibody titer in the cerebrospinal fluid in this case. The results considered the possibility of autoimmune encephalitis and immunotherapy including rituximab in cases of not only acute psychosis but also dissociation.

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