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Risk of myocardial infarction with use of selected non-steroidal anti-inflammatory drugs in patients with spondyloarthritis and osteoarthritis

Annals of Rheumatic Diseases Aug 09, 2018

Dubreuil M, et al. - Among patients with spondyloarthritis (SpA) who were prescribed non-steroidal anti-inflammatory drugs (NSAIDs), experts ascertained the myocardial infarction (MI) risk, and compared the pattern of risk in SpA with that in osteoarthritis (OA). The study included adults with incident SpA or OA who had > 1 NSAID prescription and no history of MI. They noted an increased risk of MI in SpA among the current users of diclofenac, but not naproxen. Findings suggested a difference in the MI risk with diclofeac in SpA than that in OA.

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