Pauleikhoff D, et al. - One hundred and thirty-four eyes of 70 subjects were studied to delineate the progression features of ellipsoid zone (EZ) loss in eyes with macular telangiectasia type 2 (MacTel) (as reflected by area and linear measurements) and their significance for visual acuity. At a mean annual increment of 0.057 mm², they noted significantly progression of ellipsoid zone (EZ) loss. They recorded an exponential growth before reaching a plateau as the progression rate was non-linear and interacted significantly with initial EZ lesion size. A strong heterogeneity in area sizes between fellow eyes was also reported. They observed a significant impact of the location of the EZ break on visual acuity.