Ramlakhan KP, Tobler D, Greutmann M, et al. - Because an estimated moderately elevated risk (mWHO II–III) of adverse cardiovascular, obstetric or fetal events has been noted in pregnant women with aortic coarctation (CoA), researchers used the worldwide prospective Registry of Pregnancy and Cardiac Disease (ROPAC, n=303 out of 5739) to assess pregnancy outcomes as well as associations with adverse outcomes among pregnant women with CoA. Overall 303 pregnancies (mean age 30 years, pregnancy duration 39 weeks) were analyzed. In 13 pregnancies (4.3%), the occurrence of major adverse cardiac event (MACE) was reported, of which 10 cases were of heart failure (3.3%). The occurrence of hypertensive disorders of pregnancy was noted in 16 (5.3%), their only predictor was cardiac medication use. As revealed by the ROPAC data, the rates of MACE and hypertensive disorder were low during pregnancy in women with CoA. This indicates that pregnancy is more safe as well as better tolerated as compared with previously appreciated.