Chen Y, Yang J, Su J, et al. - Via an interview-based cross-sectional study done between December 2013 and January 2014 on 20,340 individuals, researchers examined the relationship between total physical activity, physical activity in various domains and sedentary time with clustered metabolic risk in patients with T2D from Jiangsu province, China. The total, occupational and leisure-time physical activity, and sedentary time were related to clustered metabolic risk. Total physical activity, occupational physical activity and sedentary time were correlated with waist circumference, triacylglycerol, and HDL-cholesterol, although, not with systolic blood pressure. Commuting physical activity and sedentary time were significantly had a relation with triacylglycerol and fasting plasma glucose, respectively. Leisure-time physical activity was only significantly affiliated with systolic blood pressure. In conclusion, total, occupational and leisure-time physical activity had an inverse correlation with clustered metabolic risk, whereas sedentary time enhanced metabolic risk. Commuting physical activity was inversely related to triacylglycerol. Moreover, the conclusions recommend that enhanced physical activity in various domains and reduced sedentary time may have shielding influences against metabolic risk in T2D patients.