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Peripheral nervous system involvement in systemic lupus erythematosus: A retrospective study on prevalence, associated factors, and outcome

Lupus Feb 14, 2019

Bortoluzzi A, et al. - From 2000 to 2014, investigators examined 1224 cases to analyze the prevalence and clinical characteristics of peripheral nervous system involvement in a huge cohort of subjects with systemic lupus erythematosus. They noted 6.9%, the overall prevalence of peripheral nervous system involvement, with 68% of peripheral nervous system events attributable to systemic lupus erythematosus. They found polyneuropathy, the most common manifestation observed (39.2%), succeeded by cranial neuropathy (30.9%) and single (12.4%) or multiple (8.2%) mononeuritis. Candidates were noticed more prone to have higher SLEDAI-2K and SLICC/ACR Damage Index scores, as well as hypertension and livedo reticularis.
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