Lee GI, Park KA, Oh SY, et al. - Using optical coherence tomography angiography (OCT‐A), researchers conducted this exploratory retrospective cross‐sectional study to assess parafoveal and peripapillary microvascular alterations in eyes with optic neuritis (ON) along with their fellow eyes compared with healthy control eyes. They involved 31 ON‐affected eyes and 31 fellow eyes of 31 patients who had experienced unilateral ON and 33 eyes of 33 healthy controls. OCT‐A has been used to produce microvascular structural images and quantify the vessel density of the superficial retinal capillary plexus (SRCP), the deep retinal capillary plexus and radial peripapillary capillary (RPC) segments. Significant differences of SRCP and RPC segment vessel densities were observed between the three groups. After a unilateral ON episode, microvascular changes occur in both the affected eye and unaffected fellow eye.