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Patient-reported outcomes of adalimumab, phototherapy, and placebo in the vascular inflammation in psoriasis trial: A randomized controlled study

Journal of the American Academy of Dermatology Aug 14, 2019

Noe MH, Wan MT, Shin DB, et al. - Because data on the impact of narrowband ultraviolet B phototherapy on patient-reported health-related quality of life measures are limited, researchers assessed the impact of adalimumab and phototherapy on health-related quality of life. From a multicenter, randomized, placebo-controlled trial, patient-reported outcomes were examined. Every 4 weeks, the Dermatology Life Quality Index and EQ-5D-3L were assessed. Participants in the study were 97 patients (mean age was 43.5 years). Investigators found that phototherapy and adalimumab in patients with psoriasis improve both the skin-related quality of life and overall health-related quality of life vs placebo. However, phototherapy-treated patients accomplished more improvements in overall health-related quality of life vs adalimumab-treated patients.
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