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Increased pulse pressure variability within the first 24 hours leads to poor disposition in subarachnoid hemorrhage patients

American Journal of Hypertension Feb 08, 2021

Dowlati E, Triano MJ, Felbaum DR, et al. - In acute-onset subarachnoid hemorrhage (SAH), researchers sought to determine how blood pressure (BP) parameters and variability within 24 hours of hospitalization influences patient discharge outcomes. To examine associations between the primary endpoint and discharge disposition, hourly BP parameters, including systolic BP, diastolic BP, pulse pressure (PP), and their corresponding variability (delineated by standard deviation) were obtained. One hundred seventy-four SAH patients were involved in the research. On multivariate analysis, poor disposition was significantly linked to age, Hunt Hess score, intraventricular hemorrhage, and PP variability. A a poor discharge disposition for patients with aneurysmal SAH is predicted by increased variability in BP and PP within the first 24 hours of admission.

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