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In vivo corneal confocal microscopy and optical coherence tomography on eyes of participants with type 2 diabetes mellitus and obese participants without diabetes

Graefe's Archive for Clinical and Experimental Ophthalmology Jul 29, 2021

Tóth N, Silver DM, Balla S, et al. - In the present study, the researchers sought to investigate corneal nerve and retinal nerve characteristics of participants with type 2 diabetes mellitus (T2DM) vs obese participants without diabetes to discover potential nerve vulnerabilities. All candidates had a complete medical examination including a physical examination and blood sample tests. The study cohort included 83 eyes from 83 people: 44 participants with T2DM and 39 obese participants with no history of diabetes. Progression from a pre-diabetic obese state to T2DM may result in the loss or diminishment of certain corneal nerve fibers or retinal nerve fibers, but not necessarily the loss of both corneal and retinal nerve fibers at the same time. The use of in vivo corneal confocal microscopy and optical coherence tomography together allows for the monitoring of both the corneal and retinal health of the eye.

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