Mahajan S, Gu J, Lu Y, et al. – Researchers assessed hemodynamic phenotypes in a large, stable, outpatient population with hypertension on the basis of cardiac output and systemic vascular resistance. The study sample consisted of 34,238 individuals with systolic blood pressure readings of ≥ 130 mmHg who underwent impedance cardiography at 51 sites of iKang Health Checkup Centers throughout China between 2012 and 2018. Systolic blood pressure was 130–139, 140–159, and ≥ 160 mmHg in 49%, 40%, and 11% of individuals, respectively. Among individuals with systolic blood pressure 140–159 mmHg, 9,353 had high systemic vascular resistance index but normal/low cardiac index, 1,949 had a high cardiac index though low/normal systemic vascular resistance index, and 2,053 had low/normal cardiac index and systemic vascular resistance index. Moreover, cardiac index to systemic vascular resistance index ratio was negatively related to age and BMI. Overall, various hemodynamic blood pressure phenotypes were identified across all hypertensive blood pressure categories. While individual features were correlated with the cardiac index to the systemic vascular resistance index ratio, they only faintly demonstrated the difference.