Rohde S, Schwarz S, Alexandrou M, et al. - On the basis of a matched-pair analysis, the procedural and clinical results of patients who had mechanical thrombectomy (MT) under general anaesthesia (GA) or conscious sedation (CS) at two tertiary neuro-vascular centres were compared. Data of 56 individuals that were treated under CS at centre A (n = 28) were compared with selected individuals who were treated under GA at the centre B (n = 28) using a matched-pair approach. Findings revealed that there were no variations in gender, age, the site of vessel occlusion and the degree of stroke severity at baseline. In both groups, the proportion of patients with an early good clinical outcome (modified Ranking Scale ≤ 2 at discharge) was 60.4%. The time from the onset of symptoms to the start of the procedure was shorter at centre B, whereas the duration of the procedure was significantly faster at A, leading to an overall time from symptom onset to complete recanalization of 152.2 ± 68.0 min for patients treated at centre A and 171.1 ± 43.5 min for patients at centre B (ns).