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Early treatment of tuberculous uveitis improves visual outcome: A 10-year cohort study

Infection Jun 08, 2018

Anibarro L, et al. - The characteristics of tuberculous uveitis (TBU) and variables associated with visual outcome were analysed via conducting a retrospective, observational analysis in patients with presumptive TBU who were started on specific TB treatment between January 2006 and June 2016. Researchers identified 40 affected eyes of 24 individuals. Loss of visual acuity was the most frequent symptom. Posterior uveitis was the most frequent localization; at least one of the Gupta signs predictive of TBU was present in 19 patients, but no confirmed diagnoses was made. 74.4% of the eyes showed improvement in visual acuity, however, complete response was evident only in 56.4% eyes. No improvement was observed in significant association with treatment initiation ≥ 24 weeks after onset of symptoms. Observations thus highlight the significance of a prompt initiation of systemic TB treatment to improve visual prognosis.
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