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Dermatologic tacrolimus ointment on the eyelids for steroid-refractory vernal keratoconjunctivitis

Graefe's Archive for Clinical and Experimental Ophthalmology Apr 26, 2019

Liu FY, et al. - Authors analyzed 10 participants to assess the therapeutic outcomes of dermatologic tacrolimus ointment on eyelids in the treatment of refractory vernal keratoconjunctivitis (VKC). Candidates were given 0.1% dermatologic topical tacrolimus treatment on their eyelids once or twice daily for concomitant atopic dermatitis. They observed a significant decrease in the size of papillae, a reduction of discharge, improvement in hyperemia, and shield ulcer healing with re-epithelization in all cases. They also noted mild burning sensations during medication application to eyelids which disappeared a few days after treatment. About 60% of the cases were not given steroid treatment. They overall conferred the application of 0.1% dermatologic tacrolimus ointment to eyelids, an efficient and safe in the treatment of refractory VKC in subjects with concomitant atopic dermatitis.
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