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Cruciferous vegetable intake and mortality in middle-aged adults: A prospective cohort study

Clinical Nutrition Apr 29, 2018

Mori N, et al. - During this study, authors contemplated the correlation between cruciferous vegetable intake and all-cause mortality, namely cancer, heart disease, cerebrovascular disease, and injuries between 1990 and 1993 in Japan. Results demonstrated that a higher cruciferous vegetables intake was connected with reduced risk of all-cause mortality.

Methods

  • A total of 88,184 participants (age: 45-74 years) with no history of cancer, myocardial infarction, and stroke were enrolled.
  • Follow-up was for a median of 16.9 years, during which 15,349 deaths were occurred.
  • Using Cox proportional hazard regression analysis, the link between cruciferous vegetable intake and risk of all-cause and cause-specific mortality was assessed to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs), after adjustment for potential confounding factors.

Results

  • Both gender reported an inverse correlation between cruciferous vegetable intake and total mortality.
  • As per the data, HRs (95% CI) for all-cause mortality in the highest compared to the lowest quintile were 0.86 (0.80, 0.93) for men (P=0.0002 for trend) and 0.89 (0.81, 0.98) for women (P=0.03 for trend).
  • It was deduced that cruciferous vegetable intake appeared to be related to lower cancer mortality in men, along with heart disease-, cerebrovascular disease-, and injury-related mortality in women.

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