Nowacka B, et al. - In this retrospective analysis, researchers compared the structure and function of the retina and the optic nerve in patients with a history of multiple sclerosis (MS)-related demyelinating retrobulbar optic neuritis treated and not treated with systemic steroid therapy. Thirty-two eyes from 32 MS patients with a previous single episode of MS-related demyelinating retrobulbar ON were divided into 2 groups: S(+), which included 16 patients who received intravenous methylprednisolone at a dose of 1g/day for 3 days during the acute stage of ON, and S(-), which included 16 patients who did not receive any treatment. In terms of DBCVA, mean deviation of visual field macular (RT1, RT2) and RNFL thickness in the temporal, superior, nasal and inferior quadrants, as well as of the bioelectrical function (PVEP, PERG), no statistically significant differences were noted between the investigated groups. Steroid therapy should be used on an individual basis rather than as a routine treatment for each patient.