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Body mass index and body fat distribution and new-onset atrial fibrillation: Substudy of the European Prospective Investigation into Cancer and Nutrition in Norfolk (EPIC-Norfolk) study

Nutrition, Metabolism & Cardiovascular Diseases May 15, 2019

Neefs J, et al. – In this study involving participants from the European Prospective Investigation into Cancer and Nutrition in Norfolk cohort study, researchers assessed new-onset atrial fibrillation (AF) in relation to body fat distribution—measured by body mass index (BMI) and waist–hip ratio (WHR)—as well as its changes, by using adjusted sex-specific Cox proportional hazards models. A median follow-up for 19 years was performed in 10,885 men and 12,857 women, yielding 451,098 person-years. An increased risk of developing new-onset AF was observed in relation to increased body mass, as measured by BMI. Men, but not women, demonstrated an increased risk of developing new-onset AF in relation to more abdominal fat distribution, as measured by WHR.

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