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Association of insulin, C-peptide and blood lipid patterns in patients with impaired glucose regulation

BMC Endocrine Disorders Jul 19, 2019

Wang S, et al. - In this investigation involving 354 candidates, with 174 in the type 2 diabetes (T2DM) group, 112 in the impaired glucose regulation (IGR) group and 68 in the normal glucose tolerance (NGT) group, researchers examined any connections between blood glucose and lipid levels in patients with different glucose tolerance statuses, including cases of T2DM and IGR, as well as individuals with NGT. Findings revealed that basic overall percentages of glycosylated hemoglobin serum concentration for NTG, IGR and T2DM cases were 5.52%, 6.33% and 9.76%. Total cholesterol, triglycerides, and LDL-C serum concentrations were significantly higher and HDL-C concentrations were significantly lower in IGR and T2DM cases vs the NTG group. According to findings, IGR resulted in comparable unfavorable blood lipid patterns compared to T2DM patients and an insulin and C-peptide serum imbalance during an oral glucose tolerance test.

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