Parravano M, Petri D, Maurutto E, et al. - Researchers sought to determine the prevalence of depression in patients with visual impairment who regularly visit eye clinics and low vision rehabilitation services by searching MEDLINE (inception to June 7, 2020) and Embase (inception to June 7, 2020). This review identified and included studies that collected data on the relationship between acquired visual impairment and depression in people aged 18 and up. In total, 27 studies were involved in this review, and all but 2 included patients older than 65 years. The median proportion of depression was 0.30 in 1,687 patients with depression out of 6,992 total patients (mean [SD] age, 76 [13.9] years; 4195 women [60%]) with visual impairment. According to the findings of this meta-analysis, depression in patients with visual impairment is a common problem (prevalence of 25%) that should be recognized and addressed by healthcare professionals who treat these patients.