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Alterations in visual acuity and visual development in infants 1-24 months old either exposed to or infected by Zika virus during gestation, with and without microcephaly

Journal of AAPOS Sep 11, 2019

Baran LCP, da Costa MF, Vidal KS, et al. - Among 110 children (47 who had been exposed to Zika virus [ZIKV] and 63 control) from the state of São Paulo, Brazil, who were exposed to the ZIKV gestationally, researchers assessed visual acuity and visual acuity development. Participants in the study were children who had been exposed to ZIKV during gestation and age-matched control individuals received visual acuity and funduscopic examination. Findings revealed that visual acuity losses occur only in infants with gestational infection, not just exposure. Lack of age-visual acuity correlation in the ZI subgroup suggests slowing visual development even when there is no microcephaly. This outcome may have wide implications on the central nervous system for the deleterious effects of ZIKV.
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