Xu W, Ni C, Wang Y, et al. - Because the role of Galectin-1 (Gal-1) in osteoporosis has not been studied previously, researchers intended to determine if there is an association between serum Gal-1 level and bone loss. They used 6- and 18-month-old mice to create an animal model of age-related trabecular bone loss, and micro-CT was used to examine bone density and microstructure. Findings suggested an association of age-related trabecular bone loss with a decline in serum Gal-1 level in mice and men. According to the findings, Gal-1 has great potential as a biomarker for detecting bone marrow stromal cells senescence, diagnosing early osteoporosis, and monitoring trabecular bone loss.