e Silva RP, Ponte C, Lopes F, et al. - This study was undertaken to ascertain whether an alkalinized lidocaine solution is more effective than lidocaine only. Researchers enrolled individuals of both genders aged 18 or above enlisted for intradetrusor onabotulinum toxin A (BoNTA) injection (idiopathic, neurogenic, and bladder pain syndrome) in a double‐blinded randomized controlled trial after obtaining their informed consent. This analysis randomized a sum of 116 patients. The results of this study indicate that the use of an alkalinized lidocaine solution has proven to be significantly superior to lidocaine only as local anesthesia before intradetrusor BoNTA injection, implying that this may be recognized as a first‐line option.