Associations of serum uric acid with total and cause-specific mortality: Findings from individuals and pooling prospective studies

Atherosclerosis Jul 25, 2019

Mazidi M, et al. - Researchers used the National Health and Nutrition Examination Surveys (1999–2010) to prospectively assess the link between serum uric acid (SUA) and risk of total and cause specific (coronary heart disease [CHD], cerebrovascular, and cancer) mortality. To determine pooled links of SUA with all-cause and cause-specific death, they carried out a systematic review and meta-analysis of cohort studies. This study included 21,025 participants (mean age: 47.6 years; 48.7% men). A follow-up of 144 months was performed. A 10% and 8% greater risk of CHD and stroke mortality, respectively, was noted in participants in the highest quartile of SUA, according to adjusted models. The risk of total, CHD, and stroke mortality was predicted by SUA, as revealed in the meta-analysis. Overall, mortality was adversely influenced by SUA, which was especially evident in older (aged > 50 years) women.

Go to Original

Sign-up to continue reading. It is free & takes less than 2 mins

  • 45 lakhs+ doctors trust M3 globally

  • Nonloggedininfinity icon
    Free & unlimited access to original articles and quizzes
  • Nonloggedinlock icon
    Secure: we never sell your data
This article is only available to members. Are you a doctor? Click here to signup for free.
M3 app logo
Choose easy access to M3 India from your mobile!

M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen