Gallstone disease and type 2 diabetes risk: A Mendelian randomization study
Hepatology Mar 14, 2019
Wang F, et al. - A sum of 16,299 participants were researched over to examine the relationship between gallstone disease (GSD) and type 2 diabetes risk, using a Mendelian randomization analysis. Researchers diagnosed GSD by abdominal B-type ultrasound inspection and type 2 diabetes according to the criteria of the American Diabetes Association. From 2008 to 2013 ie, median 4.6 years, they recorded 1110 incident type 2 diabetes cases during 73,895 person-years of follow-up. They noted an association of each 1 SD (0.23) increment in the weighted GRS with a 17% increase of type 2 diabetes risk without statistical significance. Hence, they supported a positive but not a causal relationship between GSD and type 2 diabetes risk.
Sign-up to continue reading. It is free & takes less than 2 mins
45 lakhs+ doctors trust M3 globally
Free & unlimited access to original articles and quizzes
Secure: we never sell your data
Sign up with M3 India to try daily quizzes and take part in competitionsTry M3 India / Log In
Why join our Market Research Panel?
- 10K+ Doctors participated in 40+ Indian and Global studies in 2018
- Average honorarium per study was Rs. 1,600 and total honoraria as high as Rs. 12,000 was earned by a Doctor