Sun GZ, et al. - Researchers conducted a cross-sectional study involving 11,956 permanent residents of Liaoning Province in China ≥35 years of age, to explore if 10-year atherosclerotic cardiovascular disease (ASCVD) risk is correlated with depressive symptoms. Observations revealed a positive association of 10-year ASCVD risk with depressive symptoms in both males and females, which was more apparent in the latter. Among males vs females, significantly higher 10-year ASCVD risk (14.2 ± 10.7% vs 9.3 ± 9.1%) but lower Patient Health Questionnaire-9 (PHQ-9) score (2.34 ± 3.13 vs 3.63 ± 4.02) were evident. With advancing 10-year ASCVD risk category, a significant increase in the mean PHQ-9 score was noted in both males (from 2.03 to 2.61) and females (from 3.04 to 4.61).