1. Which of the following is the most likely cause of this patient's presentation?

• Acute pancreatitis
• Peptic ulcer disease
• Cholecystitis
• Gastric carcinoma

2. A 62-year-old woman with a history of gallstones is admitted with acute pancreatitis. Her initial presentation is severe, with elevated amylase and lipase levels. After several days of conservative management, she develops worsening abdominal pain, fever, and leukocytosis. What complication of acute pancreatitis is most likely responsible for her deteriorating condition?

• Pseudocyst formation
• Pancreatic necrosis
• Chronic pancreatitis
• Pancreatic abscess

3. A 12-year-old boy presents with recurrent episodes of abdominal pain over the past year. He reports the pain is worse after meals, particularly those high in fat. He also reports occasional episodes of loose, foul-smelling stools. His paediatrician is concerned about possible chronic pancreatitis. In addition to the symptoms described, which of the following findings would further support a diagnosis of chronic pancreatitis?

• Weight loss and poor growth
• Jaundice and dark urine
• Bloody diarrhoea and tenesmus
• Wheezing and shortness of breath

4. A 28-year-old woman at 30 weeks gestation presents to the obstetrics clinic with complaints of severe upper abdominal pain, nausea, and vomiting. She has no significant medical history, but a recent ultrasound revealed small gallstones. Considering the patient's presentation and risk factors, what is the most likely cause of her symptoms?

• Acute pancreatitis
• Pre-eclampsia
• Placental abruption
• Gastroesophageal reflux disease (GERD)

5. An 8-year-old girl presents with recurrent episodes of abdominal pain, nausea, and vomiting since early childhood. There's no family history of pancreatitis, but genetic testing reveals a heterozygous SPINK1 gene mutation. How does the SPINK1 gene mutation contribute to the development of  pancreatitis in this patient?

• It increases trypsin production leading to pancreatic autodigestion.
• It reduces the secretion of protective pancreatic enzymes.
• It leads to the formation of calcium deposits within the pancreas.
• It impairs the pancreas' ability to neutralise trypsin activity.