Ospina ML, Tong VT, Gonzalez M, et al. - In 2015 and 2016, a widespread outbreak of Zika virus was reported in Colombia. Using data from two national population-based surveillance systems for symptomatic Zika virus disease (ZVD) and birth defects, researchers sought to inscribe complementary information on the effect of the Zika virus outbreak on pregnancies and infant outcomes. During the period from June 2015 through July 2016, they identified data of 18,117 pregnant women with ZVD; among these, 5,926 (33%) had confirmed presence of Zika virus on rRT-PCR. In pregnant women with laboratory-confirmed ZVD, more common occurrence of brain or eye defects were observed in infants or fetuses during the Zika virus outbreak than during the periods immediately before and after the outbreak. Women with a symptom onset early in pregnancy had higher frequency of such defects. After the exclusion of infants or fetuses with brain or eye defects, preterm birth was reported for 8% and a low birth weight was reported for 6%. However, relative to population estimates in Colombia during 2014 (19% and 9%, respectively), these frequencies of preterm delivery and low birth weight were lower.