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Xerostomia, salivary characteristics and gland volumes following intensity-modulated radiotherapy for nasopharyngeal carcinoma: A two-year follow up

Australian Dental Journal May 01, 2018

Sim CPC, et al. - Authors assessed the changes in xerostomia status, salivary characteristics and gland volumes 2 years after radiotherapy in nasopharyngeal carcinoma patients. Findings suggested the persistence of submandibular gland volumetric shrinkage 2 years after radiotherapy. Researchers noted significantly higher xerostomia scores and significantly lower salivary flow rates and resting saliva pH, suggesting that study participants were still at risk for hyposalivation-related oral diseases. An association between parotid gland volume percent reduction and its radiation dose and between resting salivary flow rate reduction and post-radiotherapy/pre-radiotherapy SMG volume ratio were observed.
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