Sawada Y, Araie M, Shibata H, et al. - In this cross-sectional study, researchers intended to determine if there is an association between the vertical position of the central retinal vessel (CRV) within the optic nerve head (ONH) and the site of visual field defects (VFDs) in glaucoma. Using spectral-domain optical coherence tomography (exit position), the vertical position of the CRV was identified in 134 glaucoma eyes and 61 normal eyes at the point at which CRV exits lamina cribrosa onto the ONH surface. VFDs in the superior hemifields were substantially more prevalent in eyes with CRVs in the superior ONH region and vice versa. The development of glaucoma had no effect on the CRV's vertical position. The initial position of the CRV prior to the development of glaucoma may influence regional susceptibility to glaucomatous stress and may be useful in predicting the initial site of VFDs.