Perinel-Ragey S, et al. - In this study, a bench model was used to systematically explore the impact of patient-triggered modes on the size and variability of tidal volume (V_T) at different breathing frequencies (f), patient effort, and ARDS severity. Findings demonstrated a significantly reduced risk of V_T > 6 mL/kg in airway pressure release ventilation (APRV) and pressure support with guaranteed volume mode. Data showed that APRV had the highest variability. Furthermore, it was observed that pressure support with guaranteed volume could be tested in patients with ARDS.