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Value of contrast-enhanced harmonic endoscopic ultrasound for diagnosing hepatic metastases of pancreatic cancer: A prospective study

Journal of Gastroenterology and Hepatology Aug 19, 2021

Emori T, Nuta J, Kawaji Y, et al. - According to this single-center prospective study, endoscopic ultrasonography (EUS) combined with contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) has advantages over contrast-enhanced computed tomography (CE-CT) and EUS alone in terms of detecting left hepatic lobe metastases, especially small hepatic metastases, and accurate staging.

  • Thirty-one patients were found to have metastases in the left hepatic lobe.

  • EUS with CH-EUS provided a considerably greater overall detection accuracy of left hepatic lobe metastases than CE-CT and EUS alone.

  • EUS with CH-EUS outperformed CE-CT and EUS alone in detecting left hepatic lobe metastases < 10 mm.

  • After CH-EUS, the stage and/or treatment approach of pancreatic adenocarcinoma were modified in 5 of the 11 patients in whom only CH-EUS allowed detection of hepatic metastases.

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