Validation study of the Access AMH antimüllerian hormone assay for the prediction of poor ovarian response to controlled ovarian stimulation
Fertility and Sterility Apr 05, 2021
Baker VL, Glassner MJ, Doody K, et al. - Via this prospective cohort study, researchers examined the diagnostic performance of the antimüllerian hormone (AMH) level, measured utilizing the Access AMH assay, for predicting poor ovarian response (POR; defined as ≤ 4 oocytes retrieved), including the validation of the predefined AMH cutoff of 0.93 ng/mL in both serum and plasma. Data were available for 472 women (aged 21–45 years), who were planning controlled ovarian stimulation for in vitro fertilization and completed the study (74 with POR and 398 non-POR). The previously established AMH cut-point for the prediction of POR was validated in this study. As there may be variation in this cut-point depending on the assay used, they emphasize reporting the specific AMH assay in the literature whenever possible.
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