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Vaginal misoprostol vs intracervical Foley catheter for cervical ripening in postdate primigravid women: A randomized clinical trial

BMC Pregnancy and Childbirth Jul 30, 2021

Abdi N, Alavi A, Pakbaz F, et al. - One of the most common indications of labor induction is postdate pregnancy which can lead to serious maternal and fetal complications. Researchers herein performed a randomized clinical trial including 120 primigravid women aged 18–35 years with singleton, postdate pregnancies, and Bishop score ≤ 4 in order to compare vaginal misoprostol vs intracervical Foley catheter (FC) for cervical ripening in these primigravid women. The groups did not differ significantly in frequency of normal vaginal delivery, Cesarean section, meconium-stained amniotic fluid, and neonatal intensive care unit admission. Per findings, FC is linked with lower rate of placental abruption and uterine tachysystole, hence it seems to be superior to vaginal misoprostol for cervical ripening in these women. However, consideration should be given to its longer labor duration and higher oxytocin requirement.

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