Quinn-Laurin V, et al. - The purpose of this study was to analyze whether the complete removal of the complex cyst lesions with ultrasound-guided vacuum-assisted excision (US-VAE) is sufficient for their safe management when the histological diagnosis obtained at biopsy is benign. As evidence accumulates, complex cyst lesion image completely excised with US-VAE and with a benign histology at biopsy might not require further imaging follow-up or surgery and a return to routine screening can be safely recommended. Elimination of unnecessary follow-ups is pertinent given its lower cost and lesser social impact, in a world where healthcare delivery and accessibility is important.