Theuerle J, et al. - This research was designed to explore the correlations between the ACC/AHA coronary lesion classification and clinical outcomes in the contemporary percutaneous coronary intervention (PCI) era. Lower procedural success rates, as well as inferior medium-term clinical outcomes, were continuously reported in relation to PCI to more complex lesions. Therefore, pre-procedure calculation of the ACC/AHA lesion classification was still recommended in order to predict acute PCI success and clinical outcomes.