Pakozdi A, et al. - The role of repeat renal biopsy in lupus nephritis (LN) to guide treatment or predict prognosis was investigated herein. Researchers found that repeat renal biopsy essentially guided LN management, specifically in those with initial class II or V who flare. Although clinical parameters could not predict class transitions, correlation of serum creatinine level with the degree of tubulointerstitial damage was obvious.