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Ultrasonographic evaluation of ovarian mass for predicting malignancy in pregnant women

Gynecologic Oncology Sep 24, 2021

Lee SJ, Kim YH, Lee MY, et al. - In pregnant women, the Sassone scoring system or a combined model could aid in precise prediction of malignant ovarian tumors.

  • In this multicenter study, 236 pregnant women undergoing surgery for an ovarian mass were included.

  • Of these women, 223 (94.5%) had a benign ovarian mass and 13 (5.5%) had a malignant ovarian mass.

  • Benign and ovarian masses differed in six of 10 ultrasound image findings (maximal diameter of mass, maximal diameter of solid mass, wall thickness of mass, inner wall structure, thickness of septations, and papillarity).

  • Evaluation and scoring of the ovarian mass using three different scoring systems (International Ovarian Tumor Analysis Assessment of Different NEoplasias in the adnexa[IOTA ADNEX], Sassone, and Lerner), revealed significantly higher ovarian mass scores in malignant masses than in benign masses.

  • The highest area under the ROC curve (AUROC) was generated in the Sassone scoring system (AUROC: 0.831 for Sassone, 0.710 for Lerner vs 0.709 for IOTA ADNEX).

  • The six different ultrasound findings were used to develop a combined model; the AUROC of the combined model was 0.883.

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