Neumann J, et al. - Authors probed the longitudinal impacts of diabetes mellitus (DM) on cartilage deterioration over 24-months with MR-based T2 relaxation time measurements. The two study groups included, were similar in age, BMI, sex, and KL score distribution. Compared to non-diabetic controls, all compartments in diabetics, except for the patella showed a significantly higher increase in mean T2 values. A faster increase with a consistently more heterogeneous cartilage texture composition was seen with cartilage T2 values in diabetics. Results suggested that for developing early osteoarthritis with an increased degeneration of the articular cartilage in the knee, DM appeared to be a risk factor.