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Type 1 diabetes, cognitive ability and incidence of cardiovascular disease and death over 60 years of follow‐up time in men

Diabetic Medicine Feb 12, 2022

High mortality rates as well as cardiovascular outcomes for men with type 1 diabetes were revealed in this historical cohort study with 60 years of follow-up time and a less effective treatment of diabetes than today. Among males with type 1 diabetes, no difference in morbidity or mortality was found between those that had low to normal or high cognitive ability.

  • A Swedish cohort of 120 men with type 1 diabetes and 469 without type 1 diabetes was used to assess links between type 1 diabetes, diagnosed before age 18, and long-term morbidity and mortality, and to determine if cognitive ability has a role in long-term morbidity and mortality risk.

  • Dramatically higher mortality (HR 4.62), cardiovascular mortality (HR 5.60), and cardiovascular events (HR 3.97) was experienced by men with type 1 diabetes vs men without diabetes.

  • Higher cognitive ability at military conscription was found to be related to lower mortality in men without diabetes, but was not linked with any outcome in men suffering from diabetes.

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