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Two-week multimodal prehabilitation program improves perioperative functional capability in patients undergoing thoracoscopic lobectomy for lung cancer: A randomized controlled trial

Anesthesia & Analgesia Aug 21, 2020

Liu Z, Qiu T, Pei L, et al. - In patients undergoing video-assisted thoracoscopic surgery (VATS) lobectomy for nonsmall cell lung cancer, researchers evaluated how perioperative functional capacity may be impacted by a short-term, home-based, multimodal prehabilitation program. A 2-week multimodal intervention program, including respiratory training, nutrition counseling with whey protein supplementation, psychological guidance, and aerobic and resistance exercises was received preoperatively by patients in the prehabilitation group (n = 37), and usual clinical care was received by patients in the control group (n = 36) in this randomized controlled trial. Perioperative functional capacity, as measured by the 6-minute walk distance (6MWD) was the primary outcome; it was evaluated 1 day prior to and 30 days following surgery. Experts found that in patients undergoing VATS lobectomy for lung cancer, clinically pertinent improvements in perioperative functional capacity may result from a 2-week, home-based, multimodal prehabilitation program. In the prehabilitation group, the average 6MWD was 60.9 m higher perioperatively vs the control group.

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