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Trivalent car T-cells overcome interpatient antigenic variability in glioblastoma

Neuro-Oncology Oct 05, 2017

Bielamowicz K, et al. - This study addressed whether targeting 3 antigens using a single Chimeric Antigen Receptor (CAR) T-cell product can overcome interpatient antigenic variability in Glioblastoma (GBM). As per observations, universal CAR T-cells have the potential for overcoming antigenic heterogeneity in GBM and can lead to improved treatment outcomes.
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