Prasad M, et al. - In this prospective cohort study with 462 patients (median age 53 years) with non-obstructive coronary artery disease (defined as no stenosis >20% on angiography), researchers assessed the predictive impact of triglycerides and the triglyceride/high-density lipoprotein ratio on major adverse cardiovascular events. They also scrutinized the role of lipid lowering therapy in modifying this risk. Participants underwent 7.8±4.3 years of follow-up. Among those not on baseline statins, major adverse cardiovascular events in women but not in men were independently predicted by triglycerides in a Cox proportional hazard model stratified by statin use adjusting for confounders. Overall, a possible key role of triglyceride levels as a predictor of cardiovascular-specific risk was suggested for women. A possible protective impact of statin use was also suggested.