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Trends in the risk of cardiovascular disease in women with breast cancer in a Dutch nationwide cohort study

BMJ Open Jun 05, 2019

Buddeke J, et al. - Using national registry data, researchers examined trends in cardiovascular disease (CVD) risk following breast cancer. The study sample consisted of 163,881 women with in situ (7.6%) or invasive (92.4%) breast cancer, as well as women of the general population—ranging from 3,661,141 in 1996 to 4,566,573 in 2010. CVD mortality rates were calculated for the years 1996–2010 in women with and without breast cancer and hospitalization rates after breast cancer. According to findings, the absolute 10-year CVD mortality risk following breast cancer fell from 56 per 1,000 women in 1996 to 41 in 2005. This decreased from 73 per 1,000 women in 1996 to 55 in 2005 in the general population. The 5-year risk of CVD mortality for women admitted for breast cancer in 2010 vs 1996 was 42% lower.

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