Valles J, et al. - Researchers examined adult patients with community-acquired septic shock (CASS) who were admitted to the ICU at a university hospital (2003–2016), to determine the incidence and mortality as well as the impact of source control (SC) and other risk factors on the outcome. Overall 625 patients were examined. Lower mortality was seen in patients who needed SC vs those who did not. Factors related to worse outcome were severity at admission, age, alcoholism, cirrhosis, acute respiratory distress syndrome, neutropenia and thrombocytopenia, and those independently related to better survival included appropriate antibiotic treatment and adequate SC, as revealed in multivariate analysis. Throughout the study duration, an increase in CASS incidence and reduction in ICU mortality was reported. The mortality was mainly because of a reduction in mortality in infections not needing SC.